The study found that the brains of children with autism, missing key genetic markers in brain cells.
US researchers say they have found new evidence that autism begins during pregnancy and affects brain development.
First author Rich Stoner and Eric Courchesne of the Autism Center of Excellence at the University of California San Diego and Ed S. Lane Allen Institute for Brain Science in Seattle, analyzed 25 genes in brain tissue of dead children with and without autism.
These analyzes included genes that serve as a biomarker for brain cell types in different layers of the cortex, genes implicated in autism and some genes control.
"Building the baby's brain during pregnancy involves the creation of a cortex which contains six layers," Courchesne said in a statement, reports Koha.net. "We discovered a focal part of the discontinued development of these cortical layers in most children with autism".
Scientists said that such defects in part may help to explain why autism spectrum disorder is so diversified and although very small with autism show clinical improvement with early treatment and during a period of time.
"The most striking finding was similar pathology of early development in autistic brains almost the whole thing, especially considering the variety of symptoms in patients with autism, as well as extremely complex genetics behind the disease," explained Lane.
The study found that the brains of children with autism, genetic markers were missing key brain cells in multiple layers.
"This fault indicates that the decisive step early development of the creation of six distinct layers with specific types of brain cells - something that starts in life before birth - was discontinued," said Courchesne.
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